Clay Siegall leads the way in the development of antibody drug conjugates

Throughout the 1980s and early 1990s, the pace at which cancer research was moving forward began to stagnate. The huge gains of the 1950s to the 1970s began to give way to a period of lesser growth in the number of effective new treatments that were hitting the market. But for a team of researchers at Bristol-Myers Squibb, this stagnation of cancer treatment innovation would motivate them to create one of the most novel treatments ever to hit the cancer pharmaceutical industry.

Clay Siegall is one of the nation’s leading cancer researchers and one of the most successful pharmaceutical CEOs in the country today. But back in the mid-90s, Dr. Siegall was still a senior researcher at Bristol-Myers Squibb. There, he was leading a team that was developing new kinds of drugs. These were broadly termed targeted cancer therapies. The idea behind these drugs was to develop the means by which malignant tissue itself could specifically be targeted, without releasing massive quantities of highly toxic chemicals into the patient’s bloodstream.

Dr. Siegall and his team began working on a highly novel subclass of targeted therapies known as antibody drug conjugates. Antibody drug conjugates take advantage of the human body’s own immune system. By developing a large number of synthetic antibodies to the antigens produced by specific tumor types, Dr. Siegall and his team were able to find mechanisms to deliver highly lethal cytotoxins to the site of the tumor itself. Only then were the payload of toxins released into the tumor tissues, virtually eliminating all side effects associated with traditional chemotherapy, which rely on the systemic release of incredibly toxic agents.

In 1998, Dr. Siegall founded Seattle Genetics, a company dedicated solely to the production and research of new antibody drug conjugates. Throughout the 2000’s, Seattle Genetics worked to develop the first FDA-approved, viable antibody drug conjugate. In 2011, the company met its goal. ADCetris is the first FDA-approved antibody drug conjugate to hit the market. It is approved for treatment of refractory non-Hodgkin lymphoma, a disease of the immune system that causes uncontrolled production of diseased white blood cells.

This drug is currently only approved for second-line treatment of non-Hodgkin’s lymphoma. But soon, Dr. Siegall expects it to be approved for first-line treatment as well. This will mark a tectonic shift in the way that cancer is treated in the United States.

 

Talos Energy Expands Its Work In Mexico

There are many people who will find that the expansion of Talos Energy makes Mexico a better economy. This is one of the finest oil exploration companies in the world, and they have grown many times because they want to serve more people and more clients. This article explains how the company is providing the best service to those who need it. They have many oil and gas products, and they serve customers large and small.

#1: Exploration

There are many exploration locations around Mexico where someone who needs more resources may find them. The company is drilling in Mexico, and they are drilling in the Atlantic and Pacific. They are working in the Gulf of Mexico, and they will show the public that they are capable of finding the oil and gas that is needed. Exploration for the company produces quite a lot of results, and the company will give more people the products they need.

#2: Delivering To The Clients

There are many clients who need to have oil and petroleum products, and they will find that the clients need these items to be delivered as soon as possible. There are many people who will find that the company delivers on their schedule, and they hire many people to work in logistics.

#3: Creating Many Jobs

Talos Energy is a wonderful company that has a number of different jobs to offer, and there are many people who will find new jobs when they apply. the company needs people to work on oil rigs, and they will find that the company has many jobs from driving to refining. It is easier for people to find jobs because the company is so expansive.

Someone who is searching for a job in Mexico will find that they may come to Talos Energy for help. This company has created an amazing look for themselves, and they have built a profile in the country that allows them to have more customers every day. It is simple for people to receive the products they need, and they will be quite happy with the product quality.

Who Is Trusted In The Gulf Of Mexico? Talos Energy

There is a name that can be trusted to drill in the Gulf of Mexico. That company’s name is Talos Energy. They received permission from the government of Mexico to start drilling off the coast of that country. It was a very big deal because no private companies have received this honor since the oil and gas industry was nationalized there in 1938. This means that new and exciting things could be coming to the oil and gas industry very soon.

The well is called Zama-1 and it is a joint venture with two other private companies to explore the potential of the Sureste Basin. Estimates show that there may be anywhere from 100 to 500 million barrels of oil in that Basin. If companies get the chance to tap into that, they have every potential in the world to get a nice portion of that oil and make a pretty penny for themselves.

Financial experts who follow the oil and gas industry in particular are very excited about this exploration. They say that it is the one to watch when it comes to all of the projects going forward this year. It is fun to watch both because it has not happened in such a long time and also because of the massive potential that lies in that basin.

Talos Energy was among the companies that won the right to drill there in 2015 in part because of their expert knowledge of the reason. This Texas based company has worked in the Gulf for the entire time that it has been in existence. They have made it the core focus of everything that they do in business. You don’t get too many companies that have that level of knowledge. They were a clear cut favorite to win the bid.

Another good sign for those who are hopeful about future projects in this region is the very fact that Talos Energy is very committed to environmental protection. They put it up there as one of their core principles of business. Since they care about something like this, it is believed that they will do a good job on the project and hopefully earn the respect of authorities in the Mexican government. If they do, more projects like this may be forthcoming.

Find more information about Talos Energy follow them on Facebook.

Cancer Treatment Centers of America Implements the Allscripts Sunrise Program to Improve Patient Care

Cancer is not an easy disease to get rid of. As a matter of fact, research for cancer has been happening for nearly 40 years. Funding picked up for cancer research back in 1971 when former President Richard Nixon signed National Cancer Act. Since that time many cancer related organizations have sprung up to find a solution to this scourge.

The Cancer Treatment Centers of America (CTCA) has been around for 30 years. They were founded in 1988 and the institution focuses on an individualized treatment plan for each patient. Remember that each person’s cancer is different and so the CTCA tries to deal with each patient’s cancer in a unique way.

Caner Treatment Centers of America provides high quality care at an affordable cost. They ensure that patients can receive the aide they need to get better without going broke. There are many different treatment options for patients and the CTCA uses the best ones for each particular situation.

One aspect of cancer treatment has to do with patient records. This is essential to the diagnosing and treatment process. Patient records can now be accurately accessed, updated and stored on data systems. Allscripts Sunrise is the name of a software program that CTCA is now using to treat its patients.

This program has been created in conjunction with NantHealth and Allscripts. The CTCA will be using it to exchange information about patients within the system. Doctors, surgeons, physicians, treatment specialists and nurses will all be able to access patient information in a seamless flow.

They will be able to immediately access various aspects of a patient’s diagnoses, treatment plan options and their overall health history. Their insurance, financial and even mental health information will also be available on these records. CTCA will safeguard patient’s information.

The Allscripts Sunrise software system will help medical professionals to focus on the patient and not have to worry about the technical aspects of patient treatment. Many people do not understand how important the technical aspect of patient care and how critical is to treatment. Allscripts Sunrise helps to make this process easy and less complicated for CTCA care providers and their patients.

For more information follow CTCA on Twitter.

NuoDB: The Cloud Technology Game Changer

NuoDB was established in 2008 during which it was operating as NimbusDB. The brain behind the company is mainly Barry Morris who has since been the company’s CEO. His partner Jim Starkey is also well versed with technological advancements.

The main goal behind NuoDB was to create a trustworthy SQL database management systemthat enhanced the efficiency and productivity of the cloud system of computing. NuoDB has succeeded in providing the safest data management systems by passing all SQL required tests to the point of being named the new SQL.

NuoDB maintains the old SQL structure but adds to it features that boost performance for cloud systems and application. It allows programs to ‘talk’ using the SQL ‘language’ with added ACDI features to enhance communication efficiency hence better performance. NuoDB has three levels including managerial, transactional, and storing levels which enable it to allow applications especially cloud applications to run with intermixing the applications data and cache on its hard disk.

NuoDB breaks down an application’s data into ‘atoms’ which are easily stored in it’s hard disk. The database is also as equipped with multi-version concurrency systems which check an application’s data for any problems and solve them for easy access.

Talos Energy Is Poised For Greatness In The Mexican Oil Industry

Oil as a fossil fuel plays a crucial role in our everyday lives. For over eight decades the oil industry in Mexico has been State-run making it very hard for foreigners to gain entry into this lucrative energy market. Recently, the country made a bold move of permitting foreigners to do business in the oil industry. As a result of this new development, several players have positioned themselves strategically to take advantage of the opportunity.

Some of the oil industry heavyweights that are ready to reap from the liberalization of the oil industry in Mexico include Talos Energy. Under a joint venture with Mexico’s Sierra Oil & Gas and Premier Oil Plc from London, Talos Energy premiered its operations in Mexico by drilling an offshore oil well on May 21.

The offshore well named Zama-1 is located in the Sureste Basin off Tabasco State. The well is projected to hold between 100 and 500 million barrels of crude oil. According to one of Talos’ partners, Premier Oil Plc, the drilling operations at Zama-1 are expected to take 90 days, and the exercise will cost $16 million. When Mexico decided to open her oil industry to other players, the three companies bid for the exploration rights and won the first round.

Talos Energy is one of the most acclaimed companies in the global oil and gas exploration industry. The firm was started by Tim Duncan and his partners after they acquired $600 million in equity. The enterprise has the capacity of producing over 16,000 barrels of oil daily and boasts of a workforce of 120 employees.

For a short time, Talos Energy has been in operation; it has acquired several feats that were initially a preserve for seasoned players in the sector. Workplace Dynamics ranked Talos as one of the best workplaces among SME’s. According to Tim Duncan, this achievement is as a result of proper workplace policies, real structures, and an enterprise culture. Some of Talos’ equity is held by its employees from the geoscientist to the office receptionist. This strategy bolsters the sense of ownership among the team players enabling the company to deliver as a unit.

Find more information on Talos Energy on Facebook

The Ever Increasing Nexus of OSI Industries

     In our ever growing and developing world, there is that constant search for restaurants and fast food joints to meet the service of their consumers who are heterogeneously scattered around the globe. Many industries have aspired to make their services not only available in domestic markets but also to international markets in the foodservice industry. Rated as one of the top 100 American food companies, OSI industry a privately owned USA company is making giant strides into satisfying the needs of their clients through custom food product development and global food supply chain management from sourcing through processing and distribution. It is the premier global supplier of custom value-added food products to the world’s leading foodservice and retail food brands. Currently existing in 17 countries across the world, OSI industries with a facility strength of 65 and 20,000 employers offers unsurpassed and unparalleled services by supporting the presence and operations of the world foodservice and retail food brands. Through the provision of responsive and consistency service, their diligence in the delivery of daily task in the world of food services ensures that customers have a quality experience nearly anywhere in the world that they find themselves.

The ever increasing relevance and safety measures adopted by OSI industries into ensuring safe foodservice supply and the sterile environment remains their top priority. An attestation of this is the conferment of the Globe of Honour award 2016 in the United Kingdom for their demonstrated excellence in environmental safety and management.

For many in the world of business, the sky is the limit but the sky might just be the starting point for OSI Industries. Their current acquisition of Baho and Tyson food joints clearly indicate that within the next few years, their presence would be felt in every bend of the earth.

Omar Yunes: Innovatively Transforming Franchising Landscape

Running a successful franchising business calls for suave management skills and incorporation of the parent company’s ideology into the franchise. It essentially calls for the merger of two brands and ideologies including operational ideologies and goals to come up with a successful business entity capable of sustainably maximizing profits. Omar Yunes took on such a daunting task for a relatively young age of 21 years and transformed it into a business empire with 13 units and 400 employees. His excellent track record as a franchisee of the Japanese restaurant brand, Sushi Itto, was feted in 2015 with the Best Franchisee of the World (BFW) award.

The award that accepted entries from over all over the world was in recognition of the Omar Yunes’s remarkable contribution to promoting the franchise network and reputation. The 13 units he owns represent 10 percent of the company’s total franchise units. The chief executive officer of Sushi Itto, Benjamin Cancelmo, noted that Omar Yunes’s contributions have helped in transforming, innovating and remodeling the network into a better entity. He noted that such fetes are as a result of collective efforts of the employees at the various units who are dedicated to quality service delivery. The award organizers noted that his efforts have redefined how franchise and franchisee relate.

Omar Yunes’s Entrepreneurial Endeavors and Management Style

Winning the Best Franchisee of the World (BFW) award brought to the fore the excellent management skills that have become integral in Omar Yunes’s success as an entrepreneur. From a young age of 21 years, he employed an innovative approach to franchise management built on collaboration. This has ensured that the employees of his numerous franchise units are highly motivated and dedicated to delivering high quality services to the clients. The popularity of the brand encouraged him to expand his operations to three cities in Mexico. His burgeoning entrepreneurial encouraged him to invest in new industries. He expanded his portfolio to real estate industry where he owns several condominiums not only in Mexico but also in New York. This is a testimony of his excellent ability to identify profitable investment opportunities. He also founded Yandai SA and Planta de Ideas SA among others to help furthering his entrepreneurial interests.

Omar Yunes’ Franchise in Brazil Takes Wins International Awards

Omar Yunes is the brand representative of Sushi Itto in Mexico. Sushi Itto operates a food chain with the franchise in different parts of the globe. At the age of 21 years, Sushi got the opportunity to run the Mexican’s franchise of the food chain that has grown over time to 13 franchise units with branches in Mexico City, Veracruz, and Puebla. His units represent 10% of the total units owned by Sushi Itto brand.

Omar Yune Sushi won the award for his outstanding performance in his networking model. He won after an evaluation by the hotel chain on the impact of the network on the target market. According to the organizer of BFW Mexico, Diego Elizarrarras, Sushi also scooped the first place in the national qualifier. He described Sushi’s win as a reward for the efforts by the franchise to implement a working relationship with the mother company and the clients. He further attributed the success to a clean management of information that allowed for easy scrutiny of the franchise performance.

The event aims to recognize and reward efforts by the franchise in the country. The award ceremony also recognizes the contributions made by the franchisee in marketing and branding of the products as well as ideas that promote business in the country. The organizers also seek to recognize teamwork, innovation and leadership qualities in running the franchise. 34 franchisees from Mexico participated in the selection of which eight finalists were selected. The finalists proceeded to the Sushi Itto awards event featuring franchisees from different countries across the globe where Omar won selection as the best.

Omar Yunes expressed his joy and appreciation of receiving the award. He attributed the success to the outstanding performance of his team of 400 employees working in his 13 franchise units. He added that contribution of ideas by the management team and satisfactory service by the employees to his clients gave his franchise the winning combination. His win as noted by the organizers provided an expression of the developing relationship of the franchise and franchisee and increased improvement proposals generated by the teams.

Honey Birdette Expands Across A Ramge Of Sales Platforms

The Australian luxury lingerie business, Honey Birdette has recently reached a new level of success for a brand that was only established in 2006; over the course of the last year the global growth of Honey Birdette has seen the company grow in a number of valuable markets that have allowed the company to become a major force in a number of countries where this impressive brand has been building a dedicated following.

In the U.S., Honey Birdette has been seeking to grow its success as an Online retailer that reflects the large area the North American market covers, while in the U.K. Online sales are important, but a greater emphasis has been placed on physical store locations. The success that has been seen in the U.S. market has resulted in a dedicated digital platform being developed that will focus on North America, following the recent announcement of a 2016 Online sales growth of more than 370 percent in the U.S. alone.

The Honey Birdette brand is also looking to establish itself after finding itself one of the fastest growing luxury retailers in the U.K., which has resulted in the lingerie based company looking to add to the three physical location opened in 2016 in the south of the U.K. National expansion is planned that will see 40 locations available for customers across the country by the end of 2018.

The growing level of sales seen by Honey Birdette is based upon then high quality of the products available developed under the creative control of founder Eloise Monaghan, who remains an integral force in the future direction of the company.

Although the high quality of the lingerie and adult products sold attract Online sales, the development of a team of sales associates who use their skills to create a performance each day at Honey Birdette stores across the world have been important to the continued growth of the company.